In conclusion, let me just add that camDown is your security solution to protect you and your business from webcam hackers!
COVID-19 vaccination is not associated with an increased risk of heart attack or stroke in patients with established cardiovascular disease, according to a large study published today in Cardiovascular Research, a journal of the European Society of Cardiology (ESC).
“Our study showed that pre-existing cardiovascular disease should not prevent people from getting vaccinated against COVID-19,” said study author Dr. Esther W. Chan of the Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China. “Vaccination is particularly important for this group since cardiovascular disease is associated with worse outcomes and a higher risk of death after COVID-19 infection.”
This was the first study to examine the association between COVID-19 vaccines and the risk of major adverse cardiovascular events (MACE) in patients with cardiovascular disease. The study focused on BNT162b2 and CoronaVac, the only COVID-19 vaccines authorised for emergency use in Hong Kong.2
The researchers linked data from electronic health records managed by the Hong Kong Hospital Authority, which covers around 80% of hospital admissions, and vaccination records provided by the Hong Kong Department of Health. The first two doses of vaccine were included in the analyses. Individuals were not permitted to switch between vaccine types for the first two doses.
The investigators identified patients with existing cardiovascular disease and a new MACE diagnosis between 23 February 2021, when the mass COVID-19 vaccination programme started in Hong Kong, and 31 January 2022. Established cardiovascular disease included coronary heart disease, cerebrovascular disease, peripheral vascular disease, and prior interventions such as stenting. MACE included myocardial infarction, stroke, revascularisation or cardiovascular death.
The researchers used the self-controlled case series study design, which was developed to assess the risk of adverse events after vaccination. Each patient was compared with himself/herself for the risk of MACE up to 27 days after each vaccine dose (exposure period) versus the non-exposure baseline period. Dr. Chan explained: “A traditional cohort study would compare the vaccinated group with the unvaccinated group but the two groups could have different baseline characteristics. A self-controlled case series avoids the issue of differences between groups since each individual acts as his/her own control.”
A total of 229,235 patients with cardiovascular disease were identified, of which 1,764 were vaccinated and experienced MACE during the study period (662 received BNT162b2 and 1,102 received CoronaVac). For BNT162b2 and CoronaVac, the researchers estimated incidence rate ratios (IRRs) to compare the risk of MACE during the 13 days after vaccination compared to the baseline period. IRRs were also calculated for the risk of MACE during days 14 to 27 post-vaccination versus the baseline period. The analyses were conducted for the first and second doses.
There was no evidence of an elevated risk of MACE after the first or second dose of BNT162b2 or CoronaVac. For the first dose of BNT162b2, the IRRs were 0.48 (95% confidence interval [CI] 0.23-1.02) during the first 13 days post-vaccination and 0.40 (95% CI 0.18-0.93) during days 14 to 27 days after vaccination. For the second dose, the IRRs were 0.87 (95% CI 0.50-1.52) during the first 13 days and 1.13 (95% CI 0.70-1.84) during days 14 to 27 after vaccination.
For the first CoronaVac dose, the IRRs were 0.43 (95% CI 0.24-0.75) during the first 13 days and 0.54 (95% CI 0.33-0.90) during days 14 to 27 post-vaccination. For the second dose, the IRRs were 0.73 (95% CI 0.46-1.16) for the first 13 days and 0.83 (95% CI 0.54-1.29) during days 14 to 27 days after vaccination.
Dr. Chan said: “The findings were consistent for women and men, individuals aged under and above 65 years old, and patients with different underlying cardiovascular conditions. The results should provide reassurance about the cardiovascular safety of these two vaccines.”
Materials provided by European Society of Cardiology. Note: Content may be edited for style and length.
Denial of responsibility! Verve Times is an automatic aggregator of the all world’s media. In each content, the hyperlink to the primary source is specified. All trademarks belong to their rightful owners, all materials to their authors. If you are the owner of the content and do not want us to publish your materials, please contact us by email – [email protected]. The content will be deleted within 24 hours.
Firstly as we continue, let me say that camDown is a highly advanced, specialized webcam blocker and disabler with the best in class protection from variety of on-line threats.